A phase 2a study with SPL84
In a small trial, inhaled SPL84 showed promise and good tolerability in cystic fibrosis patients with a specific genetic mutation, signaling potential new treatment options.
- Lab
- Preclinical
- Early trials
- Late trials
- In practice
Urinary cell TWIST1 methylation as a non-invasive dual biomarker
A urine test detecting a specific methylation pattern identified bladder cancer with high accuracy, offering a less invasive screening option than traditional methods.
Novel or significantly improved treatmentFirst-In-Human Study of 211 At-CD45 Radioimmunotherapy With…
A new radioimmune therapy showed immediate cancer-killing activity in early human testing, though further work is needed to manage side effects safely.
Standard additionImmunoaffinity-enriched extracellular vesicle proteomics for…
Adding an extracellular vesicle protein signature to standard blood markers improved ovarian cancer detection accuracy in early research.
Standard additionGenome-Wide DNA methylation profiling of tissue-plasma pairs…
A blood test measuring eight methylation markers detected gastric cancer with strong accuracy in independent validation, suggesting promise for non-invasive screening.