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‹ Sat · 11 Apr 2026
Promising but preliminary

Platelets Outperform Leukocytes in Transcriptomic Liquid Biopsy Profiling of Myeloproliferative Neoplasms.

Platelet RNA signatures in blood could offer a simpler, more accurate way to diagnose and monitor blood cancers without tissue biopsies.

This bioRxiv preprint demonstrates that platelet RNA signatures are better than leukocyte RNA for distinguishing types of myeloproliferative neoplasms via liquid biopsy. This could improve non-invasive MPN diagnosis and monitoring.

What the study was

Study design
Comparative transcriptomic profiling
Population
Patients with myeloproliferative neoplasms
Category
Diagnostics
Maturity
Exploratory
Journal
bioRxiv

Why it surfaced

Novel liquid biopsy approach for MPN using platelet transcriptomics. Preprint caps score; needs validation.

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