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15 papers read · 13 surfaced · 0 stood out
Today's lead · Diagnostics

A circulating protein signature for predicting severe immune-related…

Blood protein patterns may help doctors predict which lymphoma patients will experience severe side effects from CAR-T therapy, enabling preventive care strategies.

Irajizad E, Fahrmann JF, Katayama H et al. · medRxiv
Read the deep dive → Read the breakdown
6/10
Impact score
How it scored
Novelty2
Clinical relevance2
Study quality1
Population & unmet need1
Time to impact (est.)
  1. Lab
  2. Preclinical
  3. Early trials
  4. Late trials
  5. In practice
Promising but preliminary

Platelets Outperform Leukocytes in Transcriptomic Liquid Biopsy…

Platelet RNA signatures in blood could offer a simpler, more accurate way to diagnose and monitor blood cancers without tissue biopsies.

bioRxiv · Score 6/10
 Standard addition

At what age should people with obesity start colorectal cancer screening?

Tailoring colorectal cancer screening age to obesity status could catch more cancers early in people at higher risk.

International journal of cancer · Score 6/10
 Promising but preliminary

Gain-of-function enhancers optimize CAR-NK cell-based anti-cancer immunotherapy.

Engineered CAR-NK cells show promise as a potentially safer, more widely available alternative to CAR-T for cancer treatment.

Immunology and cell biology · Score 5/10
 Standard addition

Targeting IL-12 for pancreatic cancer immunotherapy

New ways to deliver IL-12 directly to pancreatic tumors are advancing toward human trials, offering hope for a disease with few treatment options.

Frontiers in immunology · Score 5/10