Analysis of pleural fluid biomarkers for diagnosis of malignant pleural effusion and molecular characterization of lung cancer: a review.
Pleural fluid offers a less invasive way to diagnose lung cancer and understand its molecular features for patients unable to undergo surgical biopsy.
This review synthesizes evidence on pleural fluid as a liquid biopsy source for diagnosing malignant pleural effusion and characterizing lung cancer molecular features. The approach is particularly relevant for patients who cannot undergo surgical biopsy, representing a meaningful access improvement for a large clinical population.
What the study was
- Study design
- Review
- Population
- Lung cancer / malignant pleural effusion patients
- Category
- Diagnostics
- Maturity
- Validated
- Journal
- Current Opinion in Pulmonary Medicine
Why it surfaced
Clinical relevance high for non-surgical lung cancer patients; pleural fluid as liquid biopsy is near-term implementable but review design limits score.
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