Pulse.

a daily field guide to health research that matters

◆ Console

‹ Mon · 19 Oct 2026
Early cancer detection or prevention

Nationwide prevalence of high-risk human papillomavirus and cervical cytology findings in Chile: a registry-based study (2019-2024).

The aim of the present study was to provide the first nationwide registry-based estimate of HR-HPV positivity and age-specific cervical cytological abnormalities within the Chilean National Cervical Cancer Screening Program. Regarding PAP results, 95;63% of adequate tests were classified as negative for intraepithelial lesion or malignancy, while low-grade squamous intraepithelial lesion (LSIL) (NIE I) was found in 0;77%, high-grade squamous intraepithelial lesion (HSIL) (NIE II) in 0;33%, and severe HSIL (NIE III) in 0;26% of cases.

The aim of the present study was to provide the first nationwide registry-based estimate of HR-HPV positivity and age-specific cervical cytological abnormalities within the Chilean National Cervical Cancer Screening Program. Regarding PAP results, 95;63% of adequate tests were classified as negative for intraepithelial lesion or malignancy, while low-grade squamous intraepithelial lesion (LSIL) (NIE I) was found in 0;77%, high-grade squamous intraepithelial lesion (HSIL) (NIE II) in 0;33%, and severe HSIL (NIE III) in 0;26% of cases.

What the study was

Study design
Retrospective observational study
Population
Human participants; details are provided in the abstract.
Category
Early Detection
Maturity
Validated
Journal
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)

Why it surfaced

Retained as a 8/10 high-priority candidate for Early cancer detection (liquid biopsy, ctDNA, cfDNA); PubMed metadata and abstract were assessed conservatively.

A plain-language summary of published research — not medical advice. Talk to a clinician about your own care.