The "living well with lupus" lifestyle intervention: Effects on gut microbiota in patients with systemic lupus erythematosus and high cardiovascular risk.
Thus, the aim of the present study was to investigate the effects of a multidisciplinary lifestyle intervention on gut microbiota diversity and composition in women with SLE and high cardiovascular risk;Materials and methodsThis study analyzed a subsample (n = 31) from the "Living Well with Lupus" (LWWL) study, a 6-month randomized controlled trial. Exploratory taxonomic analyses nevertheless identified distinct relative-abundance patterns across groups and time, including a numerical increase in the Firmicutes-to-Bacteroidota (F/B) ratio in LWWL and different trajectories of several SCFA-associated genera.
Thus, the aim of the present study was to investigate the effects of a multidisciplinary lifestyle intervention on gut microbiota diversity and composition in women with SLE and high cardiovascular risk;Materials and methodsThis study analyzed a subsample (n = 31) from the "Living Well with Lupus" (LWWL) study, a 6-month randomized controlled trial. Exploratory taxonomic analyses nevertheless identified distinct relative-abundance patterns across groups and time, including a numerical increase in the Firmicutes-to-Bacteroidota (F/B) ratio in LWWL and different trajectories of several SCFA-associated genera.
What the study was
- Study design
- Randomized controlled trial
- Population
- Human participants; details are provided in the abstract.
- Category
- Public Health
- Maturity
- Validated
- Journal
- Lupus
Why it surfaced
Retained as a 8/10 high-priority candidate for Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk; PubMed metadata and abstract were assessed conservatively.
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