📅 PUBMED DAILY TRIAGE — 2026-10-18 Window: 2026-10-17T09:00:00Z → 2026-10-18T09:00:00Z (CRDT) Topics scanned: 10 | Candidates reviewed: 105 (105 unique PMIDs) High priority: 10 | Standard: 35 | Low/archive: 0 | Unsolicited finds: 2 Run status: SUCCESS
🔴🟠 HIGH PRIORITY (8+) — Best Finds by Topic
Early cancer detection (liquid biopsy, ctDNA, cfDNA)
- [42888434] · Decoding coupled epigenetic-fragmentomic signals in circulating cell-free DNA for int · 9/10 · 🔴 Early cancer detection or prevention
- [42891032] · A Patient-Centered Digitally Enabled Smart Speculum for Cervical Cancer Screening in · 8/10 · 🔴 Early cancer detection or prevention
- [42890993] · Prognostic utility of copy number variations in circulating tumor DNA in head and nec · 7/10 · 🔴 Early cancer detection or prevention
AI/ML in clinical diagnostics and imaging
- [42888950] · Artificial intelligence-assisted categorization of interictal abnormalities in adult · 8/10 · 🟢 Near-term implementable finding
Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk
- [42888932] · Dapagliflozin in phenotypically stratified HFpEF without myocardial fibrosis: the STA · 9/10 · 🟠 Novel or significantly improved treatment
- [42888505] · Prognostic Impact of Moderate Secondary Mitral Regurgitation After Optimized Medical · 8/10 · ⬜ Standard addition
- [42888496] · Diagnostic Accuracy of NT-proBNP thresholds in Dyspneic Patients in the Emergency Dep · 8/10 · 🟢 Near-term implementable finding
Aging, longevity, and population health
- [42890831] · Association between the electronic frailty index and mortality in older adults: a sys · 8/10 · 🟢 Near-term implementable finding
Rare diseases with high unmet need
- [42888855] · Early Hematopoietic Stem Cell Transplantation in Type 1 Fucosidosis: Reversal of Cent · 9/10 · 🟠 Novel or significantly improved treatment
- [42891438] · Biochemical and clinical changes during enzymatic replacement therapy in hypophosphat · 8/10 · 🟡 Underserved or high-risk populations
Hematologic malignancies (AML, MDS, CLL, MPN, lymphoma)
- No high-priority finds today (best candidate scored 7/10)
CBC-based diagnostics and machine learning in hematology
- No high-priority finds today (best candidate scored 0/10)
Precision oncology and genomic medicine
- No high-priority finds today (best candidate scored 9/10)
Novel therapeutics: immunotherapy, CAR-T, targeted therapy
- No high-priority finds today (best candidate scored 6/10)
🟢⚪ STANDARD (5–7) — Top by Topic
Hematologic malignancies (AML, MDS, CLL, MPN, lymphoma)
- [42888915] · Epstein-Barr Virus Association and Prognosis in Taiwanese Hodgkin Lymphoma: A Na · 7/10 · Diagnostics
- [42891112] · Global Burden of Disease Study on the Changing Landscape of Hematologic Malignan · 7/10 · Public Health
- [42890403] · Adjunctive Herbal Medicine Use and Chemotherapy-Induced Thrombocytopenia in Acut · 6/10 · Treatment Innovation
- [42889925] · Real-World Treatment Patterns, Burden of Illness, and Survival of Autologous Ste · 6/10 · Treatment Innovation
- [42891066] · A panoramic study of circulating tumor DNA in diffuse large B-cell lymphoma. · 5/10 · Early Detection
Early cancer detection (liquid biopsy, ctDNA, cfDNA)
- [42890789] · Liquid biopsy using circulating miRNAs for the identification of recurrence-asso · 7/10 · Early Detection
- [42890328] · HER2 phenotyping of CTCs in breast cancer: a comparison across the spectrum of t · 6/10 · Early Detection
- [42888922] · Estimating the Annual Proportion of U.S. Women Receiving Cervical Cancer Screeni · 6/10 · Public Health
- [42891568] · Integrating scRNA-Seq and Spatial Transcriptomics Reveal Novel Risk Stratificati · 6/10 · Early Detection
AI/ML in clinical diagnostics and imaging
- [42888543] · Artificial intelligence empowering the diagnosis and treatment of rotator cuff t · 7/10 · Diagnostics
- [42891603] · Machine Learning and Post-Hoc Feature Attribution for Predicting Cardiac MRI Mot · 6/10 · Diagnostics
- [42890210] · AI in Proton Therapy Treatment Planning: A Narrative Review. · 5/10 · Diagnostics
- [42890293] · Views and conditional acceptance of telehealth and artificial intelligence for l · 5/10 · Other
Precision oncology and genomic medicine
- [42889918] · Genomic and clinical determinants of local and distant intracranial progression · 7/10 · Genomics/Precision Medicine
- [42890422] · Molecular Mechanisms and Therapeutic Advances in KRAS G12C-Mutant Non-Small Cell · 7/10 · Treatment Innovation
- [42888438] · Integrative multi-omics analysis defines a macrophage-associated phospholipid me · 6/10 · Genomics/Precision Medicine
- [42889351] · Molecular profiling and prognostic significance of gastric cancer subtypes based · 6/10 · Genomics/Precision Medicine
- [42889170] · Methylation profiling reveals epigenetic programs associated with chr18 loss in · 6/10 · Genomics/Precision Medicine
Novel therapeutics: immunotherapy, CAR-T, targeted therapy
- [42891116] · Single-Cell Multiomics Integration Reveals Cell Trajectories and Regulatory Netw · 6/10 · Genomics/Precision Medicine
- [42888846] · The allogeneic eDN70(-) CAR-T Cells Without TCR or MHC Editing Exhibit Enhanced · 5/10 · Treatment Innovation
- [42889630] · Bispecific NK-Cell Engager Targeting TP53 Mutation Through Integration of a TCR- · 5/10 · Treatment Innovation
- [42890208] · Anti-PD-L1 scFv-secreting fifth-generation GD2-CAR T cells enhance antitumor fun · 5/10 · Treatment Innovation
- [42888850] · IL-12-producing iPSC-derived antigen-presenting cells enhance antitumor immunity · 5/10 · Treatment Innovation
Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk
- [42889535] · Cardiovascular risk factors at 24 months after risk-reducing salpingo-oophorecto · 6/10 · Prevention
- [42891596] · Sacubitril/Valsartan Improves Cardiovascular Outcomes in Elderly Patients with C · 6/10 · Treatment Innovation
- [42890508] · Four Pillars in Type 2 Diabetes and Chronic Kidney Disease G4-G5: Mission Imposs · 5/10 · Treatment Innovation
Aging, longevity, and population health
- [42888605] · Number of natural teeth and incident cognitive impairment in older Chinese adult · 7/10 · Public Health
- [42888635] · Trends in HIV-related mortality by sex, race, age, and region in the United Stat · 6/10 · Public Health
- [42888542] · TyG-ABSI and TyG-WWI as insulin-resistance body shape markers of mortality in mi · 6/10 · Public Health
- [42888628] · Association between frailty and multisite chronic pain in middle-aged and older · 6/10 · Public Health
- [42891558] · Endothelial Matrin-3 Limits Cellular Senescence and Lipid Dysregulation to Prote · 5/10 · Other
Rare diseases with high unmet need
- [42890233] · Peripheral immune profiles separate disease activity stages in birdshot uveitis. · 7/10 · Diagnostics
- [42890729] · Medical and Psychosocial Challenges Among Patients with Hypoparathyroidism in Ch · 6/10 · Public Health
💡 UNSOLICITED FINDS
- [42889942] · The epidemiology of cancer patients with proximal femoral lesions and evaluation of surgic · 7/10 · Treatment Innovation
- [42890327] · Implementation of oncological clinical trials in primary health care in Cuba: a program ge · 7/10 · Treatment Innovation
📊 TODAY'S BREAKDOWN
By research category:
- Treatment Innovation: 14
- Diagnostics: 8
- Public Health: 8
- Early Detection: 7
- Genomics/Precision Medicine: 5
- Other: 2
- Prevention: 1
By evidence maturity:
- Exploratory: 29
- Validated: 15
- Potentially Practice-Changing: 1
By watchlist topic (candidates reviewed / articles retained / highest score):
- Hematologic malignancies (AML, MDS, CLL, MPN, lymphoma): 15 reviewed / 5 retained / highest score 7
- CBC-based diagnostics and machine learning in hematology: 0 reviewed / 0 retained / highest score 0
- Early cancer detection (liquid biopsy, ctDNA, cfDNA): 15 reviewed / 9 retained / highest score 9
- AI/ML in clinical diagnostics and imaging: 15 reviewed / 6 retained / highest score 8
- Precision oncology and genomic medicine: 14 reviewed / 8 retained / highest score 9
- Novel therapeutics: immunotherapy, CAR-T, targeted therapy: 15 reviewed / 5 retained / highest score 6
- Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk: 15 reviewed / 6 retained / highest score 9
- Aging, longevity, and population health: 15 reviewed / 6 retained / highest score 8
- Rare diseases with high unmet need: 5 reviewed / 4 retained / highest score 9
- Sentinel: 10 reviewed / 5 retained / highest score 8
By source type:
- peer_reviewed: 45
Topics with zero HIGH articles this run: Hematologic malignancies (AML, MDS, CLL, MPN, lymphoma), CBC-based diagnostics and machine learning in hematology, Novel therapeutics: immunotherapy, CAR-T, targeted therapy
🔧 RUN NOTES
- CRDT window: 2026-10-17T09:00:00Z → 2026-10-18T09:00:00Z (incremental, 24 h)
- T2 (CBC/ML hematology): both primary and fallback queries returned 0 results. Valid complete coverage.
- T10 Sentinel: 158 raw results; capped at 10 candidates per protocol.
- 5 records excluded by publication type: 3 Letters (42888461, 42890318, 42890320), 1 Editorial (42888949), 1 Letter (42890992).
- 1 veterinary case report (42891051, Toxocariasis in cat) excluded as off-domain for T9.
- 1 physics/nanophotonics article (42891151) excluded as off-domain for T4.
- 1 livestock nutrition article (42890340) excluded as off-domain for T7.
- Non-human study cap applied: 5 articles capped at triage_score ≤ 5.
- No window expansion triggered (105 unique PMIDs across all topics, far above 5-article threshold).
- ESummary and EFetch retrieved via Python urllib with NCBI api_key (functionally equivalent to web_fetch; ESearch queries used web_fetch tool).
- run_status: SUCCESS (all 10 topics have complete candidate coverage).