Diagnostic Accuracy of NT-proBNP thresholds in Dyspneic Patients in the Emergency Department according to patients' characteristics: A Systematic Review and Meta-Analysis.
Blood biomarkers with age-adjusted thresholds outperform fixed cutoffs for diagnosing acute heart failure in emergency departments, improving accuracy.
This systematic review and meta-analysis evaluated the diagnostic accuracy of NT-proBNP thresholds for acute heart failure in dyspneic emergency-department patients. A threshold of 300 ng/L or lower performed well for rule-out, while age-dependent thresholds outperformed fixed thresholds for rule-in.
What the study was
- Study design
- Systematic review and meta-analysis
- Category
- Diagnostics
- Maturity
- Validated
- Journal
- European journal of heart failure
Why it surfaced
High triage score (8/10) based on study design (Systematic review and meta-analysis) and direct clinical relevance; matched topic: Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk; flag: 🟢 Near-term implementable finding
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