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‹ Fri · 9 Oct 2026
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Genotype-informed docosahexaenoic acid dosing based on the FADS Indel to reduce preterm and prolonged gestation: A secondary analysis of the ADORE randomized trial

Tailoring fish oil doses to a person's genes improved the chances of healthy pregnancy length in this analysis.

This PubMed-indexed secondary/post-hoc analysis of a randomized trial examined Genotype-informed docosahexaenoic acid dosing based on the FADS Indel to reduce preterm and prolonged gestation: A secondary analysis of the ADORE randomized trial. The abstract reports that analysis by retrospectively pairing high dose to I-carrier genotype and low dose to D/D was associated with the highest proportion of births at 37-40 weeks.

What the study was

Study design
Secondary/post-hoc analysis of a randomized trial
Population
Genotype-informed docosahexaenoic acid dosing based on the FADS Indel to reduce preterm and prolonged gestation: A secondary analysis of the ADORE randomized trial.
Sample size
574
Category
Genomics/Precision Medicine
Maturity
Validated
Journal
PLoS medicine

Why it surfaced

Secondary/post-hoc analysis of a randomized trial with an abstract-supported finding relevant to Precision oncology and genomic medicine; scored conservatively because only the PubMed abstract was reviewed.

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