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‹ Thu · 8 Oct 2026
Promising but preliminary

Localized Laryngeal Amyloidosis Treated With Systemic Therapy: Case Series and Literature Review

Two patients with laryngeal amyloidosis improved with immunochemotherapy, suggesting a promising new treatment path for this rare condition.

We report two adult female patients with biopsy-proven localized laryngeal amyloidosis without evidence of systemic involvement who were treated with plasma cell-directed immunochemotherapy in collaboration with ENT and head and neck surgery teams. Further study is needed to clarify patient selection, optimal treatment duration, and long-term outcomes of systemic immunochemotherapy in this rare disorder.

What the study was

Study design
Review
Population
Localized laryngeal amyloidosis is a localized plasma cell-mediated process characterized by extrace
Category
Drug Development
Maturity
Exploratory
Journal
Journal of investigative medicine high impact case reports

Why it surfaced

moderate relevance to watchlist

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