📅 PUBMED DAILY TRIAGE — 2026-10-06 Window: 2026-10-05T09:00:00Z → 2026-10-06T09:00:00Z (CRDT) Topics scanned: 10 | Unique articles reviewed: 106 | Candidates scored: 44 High priority: 7 | Standard: 37 | Low/archive: 0 | Unsolicited finds: 4 Run status: SUCCESS
🔴🟠 HIGH PRIORITY (8+) — Best Finds by Topic
Early cancer detection
PMID42833546 · Lung Cancer Screening Beyond Smoking-Based Eligibility: Evidence, Limits, and Le · 8/10 · For populations without substantial smoking history, eligibility decisions should rest on prospective evidence of reduce PMID42832577 · Role of circulating tumour DNA in predicting complete clinical response and loca · 8/10 · However, ctDNA negativity was not consistently associated with the absence of residual local disease, limiting its utili PMID42833186 · Universal Prenatal cfDNA-Single Gene Disorder Screening for Autosomal Dominant C · 4/10 · CONCLUSION: In this model, and under the assumptions specified, universal cfDNA-SGD was projected to be cost-saving and PMID42832818 · Multi-Cancer Early Detection Tests and Prostate Cancer Screening: Navigating the · 3/10 · Multi-cancer early detection (MCED) tests may create gaps and overlaps with established prostate cancer screening, requi
Sentinel
PMID42833988 · Colchicine for Prevention of Postoperative Atrial Fibrillation After Coronary Ar · 8/10 · Colchicine, an anti-inflammatory agent traditionally used in the treatment of gout, familial Mediterranean fever, and pe
Novel therapeutics: immunotherapy, CAR-T, targeted therapy
PMID42833234 · CAR T cells for autoimmune diseases: 2026 update of the EBMT-ISCT-JACIE practice · 6/10 · Autoimmune diseases are a heterogeneous group of chronic diseases characterised by loss of immune tolerance with substan PMID42833236 · Combined amivantamab, lazertinib, and bevacizumab in patients with EGFR-mutant a · 5/10 · INTERPRETATION: Combined amivantamab, lazertinib, and bevacizumab showed durable anti-tumour activity, representing a pr
Hematologic malignancies: No high-priority finds today (best candidate scored 7/10) CBC-based diagnostics and machine learning in hematology: No high-priority finds today (best candidate scored 0/10) AI/ML in clinical diagnostics and imaging: No high-priority finds today (best candidate scored 7/10) Precision oncology and genomic medicine: No high-priority finds today (best candidate scored 6/10) Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk: No high-priority finds today (best candidate scored 7/10) Aging, longevity, and population health: No high-priority finds today (best candidate scored 7/10)
🟢⚪ STANDARD (5-7) — Top by Topic
Hematologic malignancies
- PMID42832423 · Mosunetuzumab and Polatuzumab Vedotin as First-line Treatment for Larg · 7/10 · Drug Development
- PMID42833272 · Clinical outcomes were evaluated in 82 dogs with B-cell lymphoma treat · 6/10 · Drug Development
- PMID42833361 · A biomimetic nanoplatform for targeted co-delivery of ABT-199 and ATRA · 5/10 · Drug Development
- PMID42833183 · Rethinking cardiovascular risk stratification in TKI-treated chronic m · 5/10 · Diagnostics
- PMID42832892 · Advances in diagnosis and treatment of angioimmunoblastic T-cell lymph · 5/10 · Drug Development
Early cancer detection
- PMID42833723 · Follow-up colonoscopy after abnormal stool-based colorectal cancer scr · 7/10 · Early Detection
- PMID42833760 · Cervical cancer prevention in motion: national impact of the Barretos · 6/10 · Early Detection
- PMID42832730 · The Impacts of Social Marketing Campaigns on Breast Cancer Awareness a · 6/10 · Early Detection
- PMID42834009 · Race and Socioeconomic Status are Predictors of Survival in Patients W · 5/10 · Early Detection
- PMID42832834 · Racial and Gender Differences in Lung Cancer Surgery Among Black and W · 5/10 · Early Detection
AI/ML in clinical diagnostics and imaging
- PMID42833699 · Phenotypic determinants of atrial fibrillation in ischaemic stroke: a · 7/10 · Diagnostics
- PMID42833397 · Artificial Intelligence Techniques for Diagnosing and Quantifying Viti · 7/10 · Diagnostics
- PMID42833599 · Integrative multiomics and machine learning identify uridine as a cand · 6/10 · Diagnostics
- PMID42833411 · Vancomycin treatment outcomes and machine learning-based identificatio · 6/10 · Diagnostics
- PMID42833987 · Innovative holistic treatment for CKM: what lies ahead? · 5/10 · Diagnostics
Precision oncology and genomic medicine
- PMID42833159 · Oncology Nurses' Educational Needs Regarding Genomic and Genetic Tests · 6/10 · Genomics/Precision Medicine
- PMID42833294 · FGFR2/3-Altered Intrahepatic Cholangiocarcinoma: A Distinct Clinicopat · 5/10 · Genomics/Precision Medicine
- PMID42833292 · A Complementary Role for Immunohistochemistry and NGS for Detection of · 5/10 · Genomics/Precision Medicine
- PMID42833079 · Genetic characterization of two feline enteric coronaviruses in China · 5/10 · Genomics/Precision Medicine
- PMID42833024 · Multifunctional platinum(IV) prodrugs: Targeted delivery, stimuli-resp · 5/10 · Genomics/Precision Medicine
Novel therapeutics: immunotherapy, CAR-T, targeted therapy
- PMID42833860 · Poliosis predicts durable response to immune-checkpoint blockade in me · 7/10 · Drug Development
- PMID42833740 · New and Emerging Treatments of Food Allergy. · 5/10 · Treatment Innovation
Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk
- PMID42833446 · Circulating levels of glucoselysine, a fructose-specific glycation pro · 7/10 · Prevention
- PMID42833986 · Implementation of guideline-directed cardioprotective therapy in patie · 6/10 · Prevention
- PMID42833940 · Cardiometabolic benefits after adrenalectomy for mild autonomous corti · 5/10 · Prevention
Aging, longevity, and population health
- PMID42831987 · Electroacupuncture Targeting the NLRP3 Inflammasome in Senescence‑asso · 7/10 · Public Health
- PMID42832270 · Gut microbiome and healthy ageing: a systematic review of literature. · 6/10 · Public Health
- PMID42833800 · Ageism as an Upstream Determinant: A Three-Level Framework for Reframi · 5/10 · Public Health
- PMID42833705 · Assessment of the performance of primary healthcare in eight African c · 5/10 · Public Health
- PMID42832757 · AI-Based Measurement Tools for Intrinsic Capacity in Older Adults: Sco · 5/10 · Diagnostics
Rare diseases with high unmet need
- PMID42833748 · Noninfectious Signs that an Inborn Error of Immunity Might Be Lurking · 5/10 · Drug Development
- PMID42831658 · Progress in polymeric nanoparticle-based treatment approaches for Wnt · 5/10 · Drug Development
- PMID42831883 · Care Gaps in Pancreatic Enzyme Replacement Therapy: A Survey of Real-W · 4/10 · Drug Development
- PMID42831080 · Sonocavitation therapy for pancreatic cancer: Research progress, clini · 4/10 · Drug Development
Sentinel
- PMID42833997 · EUS Shear Wave Elastography for Assessing Pancreatic Fibrosis: An Expl · 5/10 · Diagnostics
- PMID42833989 · Effect of Bilateral Pectointercostal Fascial Plane Block on Chronic Po · 5/10 · Other
- PMID42833972 · Early Prediction of Insufficient Response to Ursodeoxycholic Acid: A M · 5/10 · Diagnostics
💡 UNSOLICITED FINDS
- PMID42833988 · Colchicine for Prevention of Postoperative Atrial Fibrillation After Coronary Ar · 8/10 · Drug Development
- PMID42833997 · EUS Shear Wave Elastography for Assessing Pancreatic Fibrosis: An Exploratory St · 5/10 · Diagnostics
- PMID42833989 · Effect of Bilateral Pectointercostal Fascial Plane Block on Chronic Postsurgical · 5/10 · Other
- PMID42833972 · Early Prediction of Insufficient Response to Ursodeoxycholic Acid: A Multimodal · 5/10 · Diagnostics
📊 TODAY'S BREAKDOWN
By research category: Drug Development: 10, Early Detection: 9, Diagnostics: 9, Genomics/Precision Medicine: 5, Public Health: 4, Prevention: 3, Treatment Innovation: 3, Other: 1 By evidence maturity: Potentially Practice-Changing: 8, Exploratory: 34, Validated: 2
By watchlist topic (reviewed / HIGH / best score):
- Hematologic malignancies: 15 reviewed / 0 HIGH / 7/10 best
- CBC-based diagnostics and machine learning in hematology: 0 reviewed / 0 HIGH / 0/10 best
- Early cancer detection: 15 reviewed / 4 HIGH / 8/10 best
- AI/ML in clinical diagnostics and imaging: 15 reviewed / 0 HIGH / 7/10 best
- Precision oncology and genomic medicine: 15 reviewed / 0 HIGH / 6/10 best
- Novel therapeutics: immunotherapy, CAR-T, targeted therapy: 15 reviewed / 2 HIGH / 7/10 best
- Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk: 15 reviewed / 0 HIGH / 7/10 best
- Aging, longevity, and population health: 15 reviewed / 0 HIGH / 7/10 best
- Rare diseases with high unmet need: 5 reviewed / 1 HIGH / 6/10 best
By source type: peer_reviewed 44 | preprint 0
Topics with zero 8+ articles today: Hematologic malignancies, CBC-based diagnostics and machine learning in hematology, AI/ML in clinical diagnostics and imaging, Precision oncology and genomic medicine, Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk, Aging, longevity, and population health
🔧 RUN NOTES
- No NCBI API key configured; ran at standard 3 req/sec rate limit (no api_key param).
- T2 (CBC/ML hematology): Primary query returned 0 results for today's CRDT window. No fallback triggered.
- Sentinel: 735 raw hits; top 10 selected for review; 4 were unsolicited (not matching any watchlist topic).
- Abstract coverage: 102/106 candidate PMIDs had retrievable abstracts via efetch XML; 4 PMIDs were title-only.
- Score caps applied: title-only ≤3 (1 article), preprint ≤7 (checked, none present), non-human ≤5 (1 article, animal study).
- All 106 candidate PMIDs retrieved successfully from esummary; coverage_complete=true for all topics.