📅 PUBMED DAILY TRIAGE — 2026-10-04 Window: 2026-10-03T09:00:00Z → 2026-10-04T09:00:00Z (CRDT) Topics scanned: 10 | Articles reviewed: 96 | Candidates evaluated: 0 High priority: 11 | Standard: 83 | Low/archive: 1 | Unsolicited finds: 15 Run status: SUCCESS
🔴🟠 HIGH PRIORITY (8+ or flagged) — Best Finds by Topic
Hematologic malignancies
PubMed-42828705 · Obstetric and thrombotic outcomes among pregnant patients with myeloproliferative neoplasm · 9/10 ⬜ ↳ Pregnancies in patients with MPN are associated with significantly increased maternal, obstetric, and venous thrombotic PubMed-42829271 · Changing Patterns of Causes of Death in Patients With Multiple Myeloma During the Modern T · 8/10 ⬜ ↳ As survival improves, these findings support integrating cardiovascular care, infection prevention, and long-term manage PubMed-42829161 · CAR T‑Cell Therapy as a Bridging Strategy to Second Transplant in Relapsed B‑Cell ALL · 8/10 🟠 ↳ Careful optimization of patient selection and timing of transplant remains critical to maximize long-term outcomes. PubMed-42828565 · Increased glioblastoma risk in patients with myeloproliferative neoplasms and myelodysplas · 8/10 ⬜ ↳ It lays a reliable foundation on the interactions between MPN + MDS and GBM for future research, and offers insights for
Early cancer detection
PubMed-42828040 · Minimal residual disease combined with radiological tumor volume as a tool for identificat · 7/10 🔴 ↳ CONCLUSIONS: MRD detection in NSCLC resected patients predicts relapse and poor outcome; integrating ctDNA with tumor vo PubMed-42829044 · Liquid biopsy for early detection and biomarker applications in gynecological cancers: cur · 6/10 🔴 ↳ Reported hazard ratios vary widely but differ in cohort, assay platform and sampling timepoint, and are not directly com
Novel therapeutics
PubMed-42828636 · Treatment sequence after first-line immunotherapy in older adults with advanced NSCLC (NEJ · 9/10 ⬜ ↳ However, the efficacy of single-agent chemotherapy as second-line treatment was comparable to real-world outcomes report
Precision oncology and genomic medicine
PubMed-42828659 · Reconstruction robustness of liver-referenced adaptive thresholding for 68Ga-PSMA-11 PET/C · 8/10 ⬜ ↳ Relative SUVmax-based segmentation showed substantially greater susceptibility to reconstruction changes.
Cardiovascular-metabolic
PubMed-42829171 · **Nisotirostide (LY3457263), a novel NPY2 receptor agonist for type 2 diabetes and obesity: ** · 7/10 🟠 ↳ Preclinical metabolic benefits, including weight-independent glucose improvements, translated clinically, and a manageab
Aging longevity and population health
PubMed-42827523 · Association between glycometabolic indicators and risk of early vascular aging and their p · 8/10 ⬜ ↳ The TyG index exhibited the highest observed discriminative sensitivity, while HbA1c showed the highest observed AUC.
Rare diseases with high unmet need
PubMed-42827323 · Aetiology-Specific Pancreatic Enzyme Dose Requirements and Treatment Outcomes in Pancreati · 8/10 🟢 ↳ RESULTS: Among 1015 patients, PEI was secondary to chronic pancreatitis in 496 (48.9%), pancreatectomy in 185 (18.2%), p
Sentinel
No high-priority finds today (best candidate scored 6/10)
CBC-based diagnostics and ML in hematology
No articles in this CRDT window (0 results from primary and fallback queries)
AI/ML in clinical diagnostics and imaging
No articles in this CRDT window (0 results from primary and fallback queries)
🟢⚪ STANDARD (4-7) — Top by Topic
Hematologic malignancies
PubMed-42828677 · Systemic Retinoids in Cutaneous T-Cell Lymphoma: A Scoping Review of Clinical Us · 6/10 · Treatment Innovation PubMed-42828484 · Fine-Needle Aspiration Cytology of Gingival Acute Promyelocytic Leukemia: Cytomo · 6/10 · Early Detection PubMed-42829227 · Anti-CD20 monoclonal antibodies in membranous nephropathy · 5/10 · Treatment Innovation PubMed-42828372 · Proteolysis Targeting Chimera (PROTAC) Linkerology Enhances the CDK-Degradation · 5/10 · Treatment Innovation PubMed-42829272 · Infection Prevention and Management in Patients With Multiple Myeloma Treated Wi · 4/10 · Treatment Innovation
Early cancer detection
PubMed-42829334 · Cell-free DNA fragmentomics: from chromatin biology to clinical stratification · 5/10 · Early Detection PubMed-42829094 · Kidney-specific cell-free DNA as biomarker of kidney injury: Development and exp · 5/10 · Early Detection PubMed-42829068 · When RNA Wears a Sugar Coat: Emerging Biology and Cancer Relevance of GlycoRNA · 5/10 · Early Detection PubMed-42828788 · Evaluation of optimization in digital mammography through different formulations · 5/10 · Early Detection PubMed-42828425 · Limited English Proficiency and Self-Reported Lifetime Use of Colorectal Cancer · 5/10 · Early Detection
Novel therapeutics
PubMed-42828719 · Fibrolamellar Carcinoma in the Molecular Era: From DNAJB1::PRKACA Biology to Pre · 7/10 · Treatment Innovation PubMed-42828634 · Real-World First-Line Treatment Characteristics and Physician Drivers in Advance · 7/10 · Treatment Innovation PubMed-42829067 · Targeting the Metabolic-Immune Regulator SLC35F6 Enhances Temozolomide and Anti- · 6/10 · Treatment Innovation PubMed-42828974 · Bulk and single-cell transcriptomics identify tumor-specific epithelial PSAT1 as · 6/10 · Treatment Innovation PubMed-42828692 · Atypical ovarian fibroma and thecoma mimicking malignancy: clue for differentiat · 6/10 · Treatment Innovation
Precision oncology and genomic medicine
PubMed-42829295 · Diversity within: a systematic review of intratumor heterogeneity in head and ne · 7/10 · Genomics/Precision Medicine PubMed-42828637 · Serum albumin is associated with immune-related hypothyroidism and treatment con · 7/10 · Genomics/Precision Medicine PubMed-42829010 · Engineering smart polymeric lipid nanoparticles for breast cancer: The convergen · 6/10 · Genomics/Precision Medicine PubMed-42829073 · Coupling Extracellular Vesicles with Nanomedicine for Precision Theranostics · 5/10 · Diagnostics PubMed-42828934 · "Current approaches and emerging strategies in the treatment of ductal carcinoma · 5/10 · Diagnostics
Cardiovascular-metabolic
PubMed-42829185 · Effects of corn-derived dietary fibers on cardiometabolic risk factors: a system · 7/10 · Other PubMed-42828830 · Obesity and employment: Causal evidence from Genetic Instruments in the UK Bioba · 6/10 · Treatment Innovation PubMed-42829275 · Marked Variability in Lipid Profile Reporting Among Australian Pathology Provide · 5/10 · Treatment Innovation PubMed-42829209 · A Holistic Patient-Centered Lifestyle Intervention for Health Promotion in South · 5/10 · Diagnostics PubMed-42828918 · Frailty-Related Metabolic Signature in the Association Between Frailty and Coron · 5/10 · Other
Aging longevity and population health
PubMed-42828605 · The Therapeutic Potential of MicroRNAs Delivered By Mesenchymal Stem Cells in Pa · 7/10 · Public Health PubMed-42827751 · Perceived healthy community environment and loneliness among older adults in Chi · 6/10 · Prevention PubMed-42827749 · Development and external validation of a machine learning model for three-tier d · 6/10 · Public Health PubMed-42827709 · Digital access and structural indicators of social isolation among older adults · 6/10 · Public Health PubMed-42827439 · Study on spatial accessibility and supply-demand fit of public older adult care · 6/10 · Public Health
Rare diseases with high unmet need
PubMed-42828515 · Genomic Data Governance Challenges Between Research and Clinical Care: A Scoping · 7/10 · Treatment Innovation PubMed-42827286 · A real-world study of patients with FGFR-altered advanced solid tumors after exh · 7/10 · Treatment Innovation PubMed-42829049 · Delivery architectures for oligonucleotide therapeutics in genetic and rare dise · 6/10 · Treatment Innovation PubMed-42828757 · Re-evaluating the role of IL-1Ra gene therapy in knee osteoarthritis: a case for · 6/10 · Treatment Innovation PubMed-42828162 · Sterile inflammation in LHON: mitochondrial stress, innate immune signaling, and · 6/10 · Treatment Innovation
💡 UNSOLICITED FINDS
PubMed-42828586 · Robot-assisted versus non-robotic partial nephrectomy for completely endophytic · 6/10 · Other PubMed-42828640 · Effects of exercise and educational programs on long-term quality of life, anxie · 6/10 · Diagnostics PubMed-42829343 · Premyopia Progression and Low-Dose Atropine Intervention in Children with Unilat · 6/10 · Treatment Innovation PubMed-42829312 · Remimazolam Versus Propofol During Hysteroscopy: A Systematic Review And Meta-An · 6/10 · Other PubMed-42829304 · Cold and Vibration for Pain Relief During Pediatric Venipuncture: A Quasi-Random · 6/10 · Other PubMed-42829303 · Aromatherapy for Anxiety and Pain in Radiologic and Interventional Procedures a · 6/10 · Diagnostics PubMed-42829296 · The Immunomodulatory Effect of Various Anesthetic Factors and Techniques on Pati · 6/10 · Other PubMed-42829277 · Comparative effectiveness and safety of first-line anti-TNF, vedolizumab, and us · 5/10 · Genomics/Precision Medicine
📊 TODAY'S BREAKDOWN
By research category: Treatment Innovation: 38 Other: 14 Diagnostics: 13 Early Detection: 13 Genomics/Precision Medicine: 10 Public Health: 5 Prevention: 2
By evidence maturity: Exploratory: 77 Potentially Practice-Changing: 13 Validated: 5
By watchlist topic (reviewed / kept / highest score): Hematologic malignancies: 15 reviewed / 12 kept / best score 9/10 CBC-based diagnostics and ML in hematology: 0 results in window Early cancer detection: 14 reviewed / 13 kept / best score 7/10 AI/ML in clinical diagnostics and imaging: 0 results in window Novel therapeutics: 15 reviewed / 15 kept / best score 9/10 Precision oncology and genomic medicine: 15 reviewed / 14 kept / best score 8/10 Cardiovascular-metabolic: 15 reviewed / 12 kept / best score 7/10 Aging longevity and population health: 14 reviewed / 14 kept / best score 8/10 Rare diseases with high unmet need: 8 reviewed / 8 kept / best score 8/10
By source type: peer_reviewed 95 | preprint 0
Topics with zero 8+ articles this run: CBC-based diagnostics and ML in hematology AI/ML in clinical diagnostics and imaging
🔧 RUN NOTES
- Window: CRDT 2026-10-03T09:00:00Z → 2026-10-04T09:00:00Z (1-day default; no expansion triggered)
- Sort warning: PubMed API returned 'Unknown sort schema pub+date' for all queries; sort was ignored but PMID lists were identical on retry — results accepted.
- CBC-based diagnostics and ML in hematology: Zero results from both primary and fallback queries in this CRDT window. Topic coverage complete (no candidates to review).
- AI/ML in clinical diagnostics and imaging: Zero results in this CRDT window. Topic coverage complete.
- False positives corrected: PMIDs 42828586 (robot nephrectomy → not hematologic), 42828589 (ASD → not hematologic), 42828640 (cancer survivorship QoL → not early detection), 42829277 (IBD anti-TNF → not precision oncology), 42829287 (statins in PBC → not CV-metabolic), 42828995 (forensic ethanol → completely off-topic).
- Excluded: PMID 42828691 (Letter, no abstract)
- Completely off-topic articles reclassified as unsolicited: 42828589 (ASD), 42829342 (PET plastics), 42828995 (ethanol forensic).
- Total PMIDs unique union: 96 | Fetched: 96/96 (ESummary) 96/96 (EFetch) | Missing: 0
- Run attempt: 1 of 3