Joint changes in subjective memory and objective cognition and risk of incident functional dependence: A harmonized analysis of four aging cohorts.
Combining memory complaints with objective cognitive testing identifies older adults at higher risk for losing independence, enabling earlier supportive interventions.
This large harmonized multicohort study across CHARLS, HRS, ELSA, and SHARE quantifies the joint prognostic value of subjective memory and objective cognition changes for predicting functional dependence in older adults. The finding supports combined screening assessments as a practical tool for identifying elderly at risk of functional decline.
What the study was
- Study design
- Harmonized multicohort longitudinal analysis (4 international cohorts)
- Population
- Older adults across CHARLS (China), HRS (US), ELSA (UK), and SHARE (Europe) cohorts
- Category
- Diagnostics
- Maturity
- Validated
- Journal
- Alzheimer's & dementia : the journal of the Alzheimer's Association
Why it surfaced
Multicohort harmonized analysis across four major aging studies; combined subjective-objective assessment for functional dependence is directly implementable in clinical aging assessment.
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