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‹ Tue · 18 Aug 2026
Near-term implementable finding

[Preventive effect of Saccharomyces boulardii combined with Bifidobacterium quadruple viable preparation on antibiotic-associated diarrhea in infants and young children: a prospective randomized controlled study].

Combining two probiotics reduces antibiotic-associated diarrhea in young children, offering a gentler alternative to manage this common treatment side effect.

To investigate the synergistic preventive effect of Saccharomyces boulardii combined with Bifidobacterium quadruple viable preparation (BQP) on antibiotic-associated diarrhea (AAD) in infants and young children, aiming to provide evidence for optimizing probiotic intervention strategies in clinical practice. A prospective, randomized, parallel controlled trial enrolled hospitalized children aged 1-36 months requiring antibiotic treatment from October 2023 to June 2025.

What the study was

Study design
Randomized Controlled Trial
Population
Pediatric patients
Sample size
59
Category
Other
Maturity
Potentially Practice-Changing
Journal
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics

Why it surfaced

Score 8/10: Randomized Controlled Trial, mixed model, Potentially Practice-Changing; flag=NEAR_TERM_IMPLEMENTABLE

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