Clinicopathological landscape of pediatric monomorphic PTLD: national retrospective study.
The first large cohort study of transplant lymphoma in children establishes survival benchmarks and clinical patterns, guiding care for this rare but serious complication.
This Spanish national retrospective study characterizes the clinicopathological features of pediatric monomorphic post-transplant lymphoproliferative disorder (PTLD), a rare but serious complication of transplantation with few existing large cohorts in children. The national dataset provides important outcome benchmarks for a disease that lacks prospective trial data.
What the study was
- Study design
- National retrospective cohort study
- Population
- Pediatric patients with monomorphic post-transplant lymphoproliferative disorder (PTLD) — a rare hematologic malignancy following solid organ or hematopoietic stem cell transplant
- Category
- Other
- Maturity
- Exploratory
- Journal
- Anales de Pediatría
Why it surfaced
Pediatric PTLD is a rare, serious post-transplant malignancy with scarce prospective data. National retrospective cohorts are the primary evidence source. Score 6/10: moderate novelty in pediatrics (2), relevant to rare/transplant population (2), retrospective design (1), high unmet need in rare pediatric disease (1).
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