Patient and oncologist expectations of functional prognosis among older adults with acute myeloid leukemia
An educational video and assessment tool successfully helped older leukemia patients and doctors align on realistic recovery expectations, improving shared decision-making.
This pilot RCT demonstrates substantial misalignment between older AML patients and their oncologists regarding future physical function expectations, with patients significantly more optimistic than their physicians. The UR-GOAL decisional support tool (educational video + geriatric assessment + prognostic awareness module) significantly reduced this discordance, suggesting it can improve informed decision-making in a vulnerable population.
What the study was
- Study design
- Pilot randomized controlled trial (NCT05335369)
- Population
- Adults ≥60 years with newly diagnosed AML undergoing induction therapy
- Sample size
- 77
- Category
- Treatment Innovation
- Maturity
- Exploratory
- Journal
- Blood Advances
Why it surfaced
Addresses a critical but often neglected dimension of AML care in older adults — functional expectation concordance. Pilot RCT with promising result (p=0.010) for UR-GOAL tool, though small n=77. Strong relevance for geriatric oncology pipeline.
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