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‹ Sun · 31 May 2026
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A Personalised and Gamified Digital Decision Aid for Colorectal Cancer Screening: A Randomised Controlled Pilot Study.

A digital screening tool shows limited real-world engagement, revealing that patient education and accessibility—not technology alone—are key barriers to colorectal cancer screening.

This RCT of a gamified digital decision aid for CRC screening showed no significant difference in FOBT uptake between intervention and control arms, and critically, only 1% of the target population engaged with the app, highlighting major adoption barriers for digital health screening tools. The finding of only 17% meeting informed-choice criteria reveals a substantial gap in screening literacy that digital tools alone may not bridge.

What the study was

Study design
Randomized controlled pilot trial (two-arm, smartphone app-based)
Population
Individuals born 1973–1974 invited for first CRC screening by Local Health Authority of Brescia, Italy; 248 downloaded app
Sample size
248
Category
Prevention
Maturity
Exploratory
Journal
Cancer Medicine

Why it surfaced

RCT of digital screening engagement tool; results are largely null/negative (1% app adoption) but informative for implementation research; unsolicited_find as primary match is cancer screening engagement rather than core watchlist liquid biopsy/ctDNA.

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