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‹ Mon · 25 May 2026
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Circulating CHI3L1/YKL-40 in lung cancer: Biomarker potential, analytical challenges, and clinical translation prospects.

A simple blood test for YKL-40 could help doctors track lung cancer progression once standardized testing becomes available.

Omer AB et al. reviewed the biomarker potential of circulating CHI3L1/YKL-40 in lung cancer, discussing analytical challenges and prospects for clinical translation. YKL-40 may serve as an accessible serum biomarker for lung cancer progression monitoring but requires assay standardization before widespread adoption.

What the study was

Study design
Review
Category
Diagnostics
Maturity
Exploratory
Journal
Clinica chimica acta

Why it surfaced

Clinically relevant biomarker review for lung cancer; informative but not novel enough to meet HIGH criteria.

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