Clinical implications of variant allele frequencies of genes in…
Measuring exact mutation levels alongside standard chromosome tests helps doctors more accurately predict which AML patients will benefit most from intensive versus lighter treatment.
- Lab
- Preclinical
- Early trials
- Late trials
- In practice
Postoperative MRD status Refines Recurrence Risk Stratification…
A blood test for tumor DNA three weeks after esophageal cancer surgery identifies patients at highest recurrence risk far better than current surgical pathology assessments.
Novel or significantly improved treatmentMDM2 inhibitors in myeloid cancers
A drug class blocking a cancer-protective protein shows unexpected promise specifically in myelofibrosis, opening a new disease-focused strategy after years of AML-focused research.
Novel or significantly improved treatmentMetastatic Trajectories in Non-Small Cell Lung Cancer Guide Local and…
Tracking how individual lung cancer lesions evolve separately over time could help doctors decide when to target specific tumors with radiation or surgery rather than systemic therapy alone.
Near-term implementable findingHealthy Eating Index, Epigenetic Age Acceleration and Mortality Risk…
Eating a higher-quality diet correlates with slower biological aging and longer survival, with cellular aging mechanisms explaining roughly half of this diet-longevity benefit.