Electrochemotherapy in pediatrics: a systematic review
Electric pulses combined with chemotherapy produce near-complete tumor responses in children with vascular anomalies and solid tumors.
The first systematic review of electrochemotherapy in pediatrics found complete tumor response rates of 97-100% and substantial volume reductions (52-100%) in vascular anomalies across 127 patients, with acceptable safety profiles. These results support wider adoption of ECT as a minimally invasive treatment option for pediatric solid tumors and vascular anomalies with limited alternative therapies.
What the study was
- Study design
- Systematic review (PRISMA, PROSPERO registered)
- Population
- Pediatric patients ≤18 years receiving electrochemotherapy for tumors or vascular anomalies
- Sample size
- 127
- Category
- Treatment Innovation
- Maturity
- Validated
- Journal
- European Radiology
Why it surfaced
First systematic review of ECT in pediatrics; 97-100% CR for tumors; addresses high unmet need in pediatric rare tumors and vascular anomalies; PRISMA-compliant; practice-informing.
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