Dietary total antioxidant capacity alleviates inflammatory bowel disease-related surgery, gastrointestinal cancer, and mortality risks among middle-aged and older individuals
People with inflammatory bowel disease who eat more antioxidant-rich foods show significantly fewer complications and better survival over a decade.
This large UK Biobank prospective cohort study (n=2487, 10.9yr follow-up) found that higher dietary antioxidant intake was significantly associated with fewer IBD complications, lower GI cancer incidence, and reduced mortality in middle-aged and older adults. The magnitude of risk reductions (39-61%) is clinically meaningful and suggests dietary antioxidant intake deserves integration into IBD management guidelines.
What the study was
- Study design
- Prospective cohort (UK Biobank, n=2487, median follow-up 10.9 years)
- Population
- Middle-aged and older adults with IBD from UK Biobank
- Sample size
- 2487
- Category
- Prevention
- Maturity
- Validated
- Journal
- Journal of Nutrition Health and Aging
Why it surfaced
Large prospective UK Biobank cohort with long follow-up, robust HRs across three clinically important outcomes (surgery, cancer, mortality), gene-diet interaction data adds mechanistic depth; dietary guidance is immediately actionable in clinical practice.
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