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‹ Wed · 1 Apr 2026
Near-term implementable finding

Minimal residual disease guided treatment approaches in non-Hodgkin lymphoma-Where we are and where we're headed.

Blood-based tests now predict treatment outcomes in lymphoma better than imaging, helping doctors tailor therapy intensity to individual risk.

This review covers how ctDNA-based MRD assessment is transforming NHL treatment decisions, with ctDNA outperforming PET for outcome prediction in DLBCL. Prospective trials are testing MRD-guided therapy de-escalation across NHL subtypes.

What the study was

Study design
Review
Population
Patients with non-Hodgkin lymphoma
Category
Diagnostics
Maturity
Validated
Journal
Seminars in Hematology

Why it surfaced

Comprehensive review from NCI on MRD-guided treatment in NHL — highly relevant to hematologic malignancies and liquid biopsy watchlist. Review type limits design score.

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